You can add the ledger in the Metamask menu, under Add Hardware Wallet. Then you can do everything with the ledger via Metamask. Connect every side, buy, sell, incl. NFTs. Of course, you then have to confirm everything with Ledger. I recommend this to everyone as the standard security in Metamask. Of course, you then have to send all coins and NFTs from your existing Metamask wallet to the Ledger, if you haven't already done this before, and then only work with the Ledger. The transfer costs something, but is very cheap to the ledger. I learned the hard way with a hacked Metamask wallet, only because I once connected Metamask to a fake site and then everything was gone. Since then, I've only used Ledger, Metamask or whatever else!

You can add the ledger in the Metamask menu, under Add Hardware Wallet. After that, you can do everything via the ledger. Connect every side, buy, sell, incl. NFTs. Of course then confirm everything with Ledger. I recommend this to everyone as the standard security in Metamask.